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August 1, 2025Cancer Management and ResearchOpen Access

Circ_0061825 Acts as a miR-593-3p Sponge to Promote Breast Cancer Progression by Regulating FGFR3 Expression [Retraction]

Jiping Xie Yi Wan Min Zhang Zeyu Jin Yongqiang Yao

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Key Points

The research suggested that circ_0061825 promotes breast cancer progression.
Key evidence pointed to the involvement of fgfr3 in this regulatory mechanism.
The study employed observational analysis to assess the interaction of circRNA and miRNA in breast cancer cells.
This retraction underscores the need for careful validation in cancer research.

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Implication

Retraction highlights the role of circ_0061825 as a mir-593-3p sponge in breast cancer, suggesting implications for treatment.

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Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/68c1b81f54b1d3bfb60ec827 https://doi.org/10.2147/cmar.s558488

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterization of Circ_0048766: an oncogenic circular rna promoting triple-negative breast cancer progression via the miR-329-3p/CXCR4 axis and regulated by METTL3Original Research · 2026
2Inhibiting circ_0000673 blocks the progression of colorectal cancer through downregulating CPSF6 via targeting miR-548b-3p2024
3[Retracted] Regulation of miR‑155 affects the invasion and migration of gastric carcinoma cells by modulating the STAT3 signaling pathway2025
4circEFR3A promotes breast cancer progression by sponging miR‑590‑3p to upregulate androgen receptor expression2025 · 1 citations
5Circular RNA-0001283 Suppresses Breast Cancer Proliferation and Invasion via MiR-187/HIPK3 AxisOriginal Research · 2020 · 23 citations

More related papers

The novel circ_0004674/<scp>miR</scp>‐139‐5p/<scp>ZBTB2</scp> regulatory cascade inhibits the development of oral squamous cell carcinoma2024
Retraction: MiRNA-200b regulates RMP7-induced increases in blood-tumor barrier permeability by targeting RhoA and ROCKII2025
Retraction Note: MiR-221 inhibits proliferation of pancreatic cancer cells via down regulation of SOCS3.2024

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