What type of study is this?

This is a Narrative Review study (also classified as: Animal Study).

DNA Methylation in Bladder Cancer: Diagnostic and Therapeutic Perspectives—A Narrative Review

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Narrative review highlights the role of dna methylation and tumour suppressor genes in bladder cancer, suggesting new diagnostic methods.

DNA methylation plays a crucial role in bladder cancer development, altering gene expression and enabling malignancy.
Promoter hypermethylation leads to transcriptional silencing of key tumour suppressor genes, contributing to uncontrolled cell growth.
Urine-based DNA methylation assays provide a non-invasive method for early bladder cancer detection with high specificity.
Animal models provide essential insights into methylation dynamics and gene-environment interactions in bladder cancer research.

Puia et al. (2025) studied this question.

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View Full Paper

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Authors

Narrative review highlights the role of dna methylation and tumour suppressor genes in bladder cancer, suggesting new diagnostic methods.

DNA methylation plays a crucial role in bladder cancer development, altering gene expression and enabling malignancy.
Promoter hypermethylation leads to transcriptional silencing of key tumour suppressor genes, contributing to uncontrolled cell growth.
Urine-based DNA methylation assays provide a non-invasive method for early bladder cancer detection with high specificity.
Animal models provide essential insights into methylation dynamics and gene-environment interactions in bladder cancer research.

Puia et al. (2025) studied this question.

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