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September 10, 2025Journal of Healthcare Sciences

The Role of Minimal Residual Disease (MRD) in Predicting Relapse in Acute Leukemia

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Authors

NMNoor Adel MerwassSalmaniya Medical Complex YAYasser Abdulrhman AlnaeemImam Mohammad ibn Saud Islamic University ZAZahra Malik AlsadiqKing Saud Medical City

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Implication

This review demonstrates the association of minimal residual disease with relapse risk in acute leukemia, highlighting the role of advanced detection methodologies.

Key Points

MRD status is a significant predictor of relapse risk and overall survival in acute leukemia patients.
Utilizing techniques like real-time quantitative polymerase chain reaction and next-generation sequencing enhances MRD assessment.
Assessing MRD at key timepoints informs risk-adapted therapies and decisions for hematopoietic stem cell transplant.
Technological advancements have improved standardization in MRD assessments, though challenges remain.

Cite This Study

Merwass et al. (2025) studied this question.

synapsesocial.com/papers/68c1bb5b54b1d3bfb60ecd3a https://doi.org/10.52533/johs.2025.50711

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Implication

This review demonstrates the association of minimal residual disease with relapse risk in acute leukemia, highlighting the role of advanced detection methodologies.

The Role of Minimal Residual Disease (MRD) in Predicting Relapse in Acute Leukemia

Discussion

Member takes

Implication

Key Points

Cite This Study

The Role of Minimal Residual Disease (MRD) in Predicting Relapse in Acute Leukemia

Discussion

Member takes

Implication

Key Points

Cite This Study

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