Crinum asiaticum L. bulb extracts as a potential source of novel antimicrobial agents: An in-vitro study

This study evaluated the antimicrobial potential of C. asiaticum bulb extracts from three different areas (KGVA 1, KGVA 2, and KGVA 3) against clinically relevant bacteria and fungi. The aqueous and hydrated methanol extracts of C. asiaticum bulb showed broad-spectrum antibacterial activity against certain bacterial species, including Escherichia coli, Proteus sp, and Pseudomonas aeruginosa. The hydrated methanol extract of KGVA 2 showed significant antibacterial activity against Pseudomonas aeruginosa, with a zone of inhibition of 22.7±0.29mm at 80µl. The aqueous extract of KGVA 3 exhibited broad-spectrum antifungal activity against Aspergillus species, including A. flavus, A. fumigatus, and A. niger. The hydrated methanol extract of KGVA 1 showed significant antifungal activity against A. niger, with a zone of inhibition of 25.1±0.15mm at 80µl. These findings suggest that C. asiaticum bulb extracts have potential antimicrobial properties, making them a promising source for the development of novel antimicrobial agents.