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January 1, 2025Evidence-based Complementary and Alternative MedicineOpen Access

RETRACTION: Echinacoside Protects Against 6‐Hydroxydopamine‐Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production

Evidence-Based Complementary and Alternative Medicine

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Key Points

Echinacoside significantly protects against mitochondrial dysfunction linked to 6-hydroxydopamine exposure.
Key evidence shows reduced ROS production in PC12 cells treated with echinacoside.
Observational analysis on inflammatory responses in PC12 cells reveals reduced levels after echinacoside treatment.
These findings emphasize the need for careful evaluation, as retraction suggests previously reported results may not be reliable.

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Implication

Retraction reveals how echinacoside reduces mitochondrial dysfunction and inflammation in PC12 cells, suggesting a potential therapeutic role.

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Cite This Study

Evidence-Based Complementary and Alternative Medicine (2025) studied this question.

synapsesocial.com/papers/68c1bb6354b1d3bfb60ed296 https://doi.org/10.1155/ecam/9891208

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2RETRACTION: Resveratrol Downregulates Interleukin-6-Stimulated Sonic Hedgehog Signaling in Human Acute Myeloid Leukemia.Original Research · 2026
3<p>Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic <em>Db/Db</em> Mice</p>preclinical · 2020 · 20 citations
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5RETRACTION: Ameliorative Effects of Scopoletin from <i>Crossostephium chinensis</i> against Inflammation Pain and Its Mechanisms in Mice.Original Research · 2026

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