Case report reveals spontaneous lens dislocation in a 50-year-old female, highlighting microspherophakia implications.
Microspherophakia is a rare abnormality of the crystalline lens, marked by reduced equatorial diameter and increased lens thickness. We report a rare case of spontaneous anterior dislocation of a cataractous microspherophakic lens in a 50-year-old non-syndromic female who presented with sudden, painless vision loss in the right eye. Slit-lamp examination revealed a small, spherical lens dislocated into the anterior chamber, with no signs of trauma or inammation. Systemic assessment revealed no features suggestive of associated syndromes such as Marfan or Weill–Marchesani. The patient underwent successful intracapsular lens extraction followed by retropupillary iris-claw intraocular lens implantation, resulting in a best-corrected visual acuity of 6/12. Family screening identied bilateral microspherophakia in her son, indicating a likely hereditary etiology. This case highlights the importance of recognizing isolated microspherophakia as a potential cause of spontaneous lens dislocation in adults and emphasizes the value of timely surgical intervention and family evaluation.
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Shah et al. (2025) studied this question.
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