Case report highlights rare pituitary metastasis in lung cancer patient, indicating potential diagnostic challenges.
Lung cancer is the leading cause of cancer and cancer-related deaths, and India ranks the fourth highest country. Lung cancer is a highly aggressive malignancy with a tendency for rapid progression, making early detection and prompt treatment essential for improving patient outcomes. Lung cancer can spread locally into surrounding tissue as well as travel through lymphatics to other parts of the body, most often to bone, brain, liver, and adrenal glands. Metastasis to pituitary and pineal glands is extremely rare. The differential diagnosis for pituitary metastasis could be pituitary adenoma where lesion usually lies at the anterior aspect of pituitary fossa, whereas metastasis is seen at the posterior aspect. There is a paucity of published literature, with only a few cases reported of pituitary and pineal gland metastasis. Hence, to add to the literature, we present a case of pituitary metastasis in an older woman with lung cancer.
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Mandal et al. (2025) studied this question.
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