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September 10, 2025CephalalgiaOpen Access

Real world effectiveness of anti-CGRP monoclonal antibodies over three consecutive one-year treatment cycles: An intention-to-treat analysis

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Authors

GVGloria VaghiMCMichele CorradoMPMaria Magdalena Pocora

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Overview

Prospective analysis shows consistent reduction in monthly migraine days in chronic migraine patients, highlighting ITT findings.

Key Points

  • A sustained reduction in monthly migraine days was observed across three treatment cycles.
  • After three treatment cycles, the 50% response rate was 38.5%, indicating varying effectiveness.
  • ITT analysis demonstrated the ongoing high burden of disease despite treatment efficacy.
  • The study suggests the necessity for exploring additional treatment approaches beyond anti-CGRP.

Cite This Study

Vaghi et al. (2025) studied this question.

synapsesocial.com/papers/68c1bb7854b1d3bfb60edd1ehttps://doi.org/10.1177/03331024251353421
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