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Case study describes tetraparesis and encephalopathy in a patient with influenza B, suggesting immunological triggers.
In this case study, we present an unusual course of a 40-year-old patient with clinical signs of a viral infection with leading gastrointestinal symptoms. In the short term, he developed a progressive ascending sensorimotor tetraparesis with autonomic symptoms as well as qualitative disturbance of consciousness and the need for intensive medical care. Imaging revealed transverse myelitis and a diffusion disorder of the splenium (so-called CLOCC lesion). A diagnosis of "mild encephalopathy with reversible splenial lesion (MERS)" and "longitudinally extensive transverse myelitis (LETM)" was made. An influenza B infection was diagnosed as the causative disease. This is an immunologically triggered pathogenesis. Immunosuppressive therapy indicated.
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Pletzer et al. (2025) studied this question.
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