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September 10, 2025Discover OncologyOpen Access

Advances and emerging trends in the tumor microenvironment of colorectal cancer liver metastasis: a bibliometric analysis

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Authors

QWQiong WuChangsha Central HospitalJZJie ZhaoHandan CollegeZSZhongqi SunHarbin Medical University

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Overview

Bibliometric analysis reveals emerging trends in tumor microenvironment and CRLM research, indicating greater collaboration across nations.

Key Points

  • Dynamic interplay of cellular subtypes in the tumor microenvironment affects treatment and prognosis.
  • China and the USA show significant collaboration in research output related to CRLM.
  • Key research trends revolve around tumor microenvironment, with immune-related keywords on the rise since 2020.
  • Future research will prioritize understanding TME evolution post-treatment and identifying new therapeutic targets.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd2a54b1d3bfb60ee0achttps://doi.org/10.1007/s12672-025-03292-7
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Also Consider

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  1. 1A bibliometric and visual analysis of colorectal cancer liver metastasis research from 2015 to 20252026
  2. 2The trends and hotspots of immunotherapy for metastatic colorectal cancer from 2013 to 2022: A bibliometric and visual analysis2024 · 3 citations
  3. 3Key molecular mechanisms and regulatory networks in colorectal cancer liver metastasis2026
  4. 4Mapping the global intellectual landscape of inflammatory tumor microenvironment in colorectal cancer pathogenesis and prognostic research since this century2025
  5. 5A bibliometric study on microenvironment-mediated drug resistance in interventional liver cancer treatment2025