What type of study is this?

September 10, 2025Scientific ReportsOpen Access

Glucose stimulated CEST MRI pHe mapping for improved differentiation of tumors with altered hypoxia inducible factor 1alpha expression

View Full Paper

Ask AI

Bookmark

Authors

Observational analysis showed glucose enhances pHe mapping in triple-negative breast cancer, indicating improved tumor differentiation.

Enhanced differentiation in pHe maps was observed following glucose administration in tumors with different HIF-1α expression.
Mean pHe values differed across tumor types, with significant results following glucose stimulation compared to non-stimulated conditions.
CEST MRI was used to map extracellular pH, demonstrating its potential in characterizing tumor phenotypes with altered HIF-1α expression.
The findings support using glucose stimulation for improved diagnostic imaging strategies in evaluating tumor aggressiveness.

Singh et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark