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September 10, 2025

Combination of chemotherapy and allogeneic hematopoietic stem cell transplantation for elderly patients with blastic plasmacytoid dendritic cell tumor: a case report and literature review

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Authors

CYCao YuezhenNGNa GaoGWGu Wenrong

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Overview

Case report reveals improved outcomes of BPDCN treatment using chemotherapy and allogeneic transplant, suggesting potential strategies for this rare disease.

Key Points

  • This case report shows promising results in treating blastic plasmacytoid dendritic cell neoplasm in an elderly patient.
  • The patient exhibited skin lesions as primary symptoms, alongside significant hematological manifestations.
  • Therapy included chemotherapy followed by allogeneic hematopoietic stem cell transplantation, which may improve prognosis.
  • This case highlights the necessity for increased awareness and understanding of diagnosing BPDCN among clinicians.

Cite This Study

Yuezhen et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd4254b1d3bfb60ee97ehttps://doi.org/10.21203/rs.3.rs-6975704/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blastic Plasmacytoid Dendritic Cell Neoplasm: A Rare Case Report2026
  2. 2Blastic plasmacytoid dendritic cell neoplasm: Two case reports2024 · 1 citations
  3. 3Diagnosing and Treating Blastic Plasmacytoid Dendritic Cell Neoplasm in a Resource-Limited Setting2024 · 4 citations
  4. 4Blastic Plasmacytoid Dendritic Cell Neoplasm: A Dermatological Window for Early Diagnosis2026
  5. 5A Case of Cutaneous Blastic Plasmacytoid Dendritic Cell Neoplasm on the Chest2024