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September 10, 2025Urology AnnalsOpen Access

Circulating microRNAs as biomarker in prostate cancer and their significance in the differentiation of benign and malignant conditions of the prostate

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Observational analysis revealed distinct circulating mirna expression patterns in prostate cancer, indicating potential for improved biomarkers.

Circulating miRNAs show promise as minimally invasive biomarkers for prostate cancer.
Notably, miR-1272 and miR-1247-5p were significantly up-regulated, while others were down-regulated.
Analysis used NanoString Human MicroRNA Arrays on serum samples from localized and metastatic prostate cancer patients.
Findings suggest miRNAs could enhance diagnostic accuracy, but further validation in larger cohorts is necessary.

Kowsalya et al. (2025) studied this question.

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Observational analysis revealed distinct circulating mirna expression patterns in prostate cancer, indicating potential for improved biomarkers.