Effectiveness of platelet-rich fibrin (PRF) block graft in managing intra-bony defects: A case report

Periodontal disease is a multifactorial condition affecting tissues and supporting bone, potentially leading to tooth loss. Therefore, it is of interest to remove inflammatory tissues and restore health, utilizing techniques like guided tissue regeneration, bone grafts, and root surface bio-modifications. Platelet-rich fibrin (PRF) is a promising biomaterial due to its autologous nature and regenerative potential. This case report evaluates PRF block grafts in managing intra-bony defects, assessing pocket depth reduction, attachment level gain, and radiographic bone fill. The results showed significant clinical and radiographic improvements suggest PRF block grafts as an effective modality for periodontal regeneration. Data shows PRF as a viable alternative to conventional grafting materials. PRF may enhance healing and improve periodontal prognosis in treating intrabony defects.