Application of Nanotechnology in Treatment of Nematodes Diseases: A Review Article

Background: Nematodes were among the first known human pathogens, and many efforts have been made to develop treatments for them. These infections impose a heavy burden on human populations, especially the poor. Nowadays, intervention and treatment programs have been initiated to control and treat onchocerciasis, lymphatic filariasis, gastrointestinal nematodes, and soil-transmitted helminths. Nanotechnology is being used as a dynamic and dynamic tool in research for the treatment of diseases. Here, we review the application of nanotechnology in treatment of nematode diseases. Methods: This narrative review was conducted using scientific sites such as Medline, Pubmed Science Direct, and Springer Link databases covering 2000 to 2025 to investigate the application of nanotechnology in nematodes diseases treatment. The terms used included: nanotechnology, nanoparticles, nematodes, nematodes treatment, and nanodrug. Results: Twenty-eight full-text articles were assessed for eligibility, and from them, 23 selected studies on the application of nanotechnology in the treatment of nematode diseases were selected. Conclusion: The nanodrugs and nanomedicines are future sources for the development of new drugs with therapeutic applications. Nanotechnology has the potential to be used as antinematodal drugs by modifying the biodistribution of drugs and improving bioavailability.