Diagnostic Accuracy of DW-MRI in Detecting Parametrial Invasion in Cervical Cancer Patients, Taking Histopathology as Gold Standard

Introduction: When it comes to separating locally progressed or late-stage illness, that needs chemoradiotherapy, from early-stage disease that can be treated surgically, MRI plays a crucial role. Prognostic variables which include tumor size, parametrial infiltration, pelvic wall invasion, adjacent organ invasion, and lymph node metastases are also evaluated by MRI. Study Design: Cross-sectional (validation) study. Settings: Radiology Department of Shaukat Khanum Memorial Hospital, Lahore. Methodology: The study comprised 141 cervical cancer patients with ages ranging from 20 to 60. Patients with contraindications for MR imaging and women with a history of cervical cancer treatment, including surgery, chemotherapy or radiation were not included. Diffusion weighted magnetic resonance imaging was performed on each patient. The histopathological report was linked with the DWI-MRI data. Results: In my study, DW-MRI sensitivity was (89.86%), specificity (88.89%), PPV (88.57%), NPV (90.14%) and diagnostic accuracy (89.36%) in detecting parametrial invasion in cervical cancer patients. Conclusion: According to the study's findings, DW-MRI is an extremely sensitive and precise imaging technique for identifying parametrial invasion in patients with cervical cancer.