What type of study is this?

This is a Genome Sequencing study (also classified as: Phylogenetic Analysis, Observational).

September 10, 2025Frontiers in MicrobiologyOpen Access

The pre- and post-COVID-19 pandemic dengue fever patterns in southeastern coastal China in 2019 and 2024: molecular evolution and strain replacement

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Complete genotype turnover of DENV-1 occurred, with strain 1I_K.2 replacing 1I_E.1 between 2019 and 2024.
Phylogenetic analysis revealed distinct clades for DENV-1 isolates from 2019 and 2024, highlighting significant evolution.
Eighteen recombination events were detected, primarily involving DENV-1 strains from Vietnam and Cambodia.
Observed antigenic divergence between isolates emphasizes the need for ongoing genomic monitoring in regional dengue control.

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Observational analysis identified complete genotype turnover of DENV-1 in southeastern coastal China, indicating shifting strain dominance.

Zhang et al. (2025) studied this question.

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Observational analysis identified complete genotype turnover of DENV-1 in southeastern coastal China, indicating shifting strain dominance.