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September 10, 2025World Journal of Psychiatry

Application and efficacy of quetiapine in patients with high-risk factors for bipolar disorder: A randomized controlled trial

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Authors

LLLianlian LeiUniversity of Michigan CGChenjie GeThird People's Hospital of Huzhou HWHong WangNortheast Agricultural University

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Implication

Randomized controlled trial shows quetiapine improves symptoms in patients with anxiety disorder, implying better treatment strategies for bipolar disorder.

Key Points

Combining quetiapine with sertraline significantly reduces anxiety and depressive symptoms in patients with high-risk bipolar disorder.
Group B, receiving quetiapine, showed significantly lower scores on the Hamilton anxiety scale compared to Group A by week 24.
Efficacy assessments included the Hamilton anxiety scale and Hamilton depression scale, indicating robust evaluation measures.
The treatment combination suggests rapid relief of symptoms, highlighting the need for tailored therapy approaches in high-risk bipolar patients.

Cite This Study

Lei et al. (2025) studied this question.

synapsesocial.com/papers/68c1c9d254b1d3bfb60f2bab https://doi.org/10.5498/wjp.v15.i8.104221

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Implication

Randomized controlled trial shows quetiapine improves symptoms in patients with anxiety disorder, implying better treatment strategies for bipolar disorder.

Application and efficacy of quetiapine in patients with high-risk factors for bipolar disorder: A randomized controlled trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Application and efficacy of quetiapine in patients with high-risk factors for bipolar disorder: A randomized controlled trial

Discussion

Member takes

Implication

Key Points

Cite This Study

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