Observational analysis demonstrates enhanced biocompatibility and antioxidant properties in gold nanoparticles, highlighting green synthesis potential using Syzygium samarangense.
Nanotechnology has revolutionized various industries with gold nanoparticles (AuNPs) being particularly significant due to their biocompatibility and versatile applications. Traditional synthesis methods for AuNPs often involve harsh chemicals, raising concerns about environmental sustainability. Using leaf extract from Syzygium samarangense as a reducing agent, this work investigates the green synthesis of AuNPs which provides a more environmentally friendly technique. The leaf extract's abundant phytoconstituents, such as phenolic acids and flavonoids, stabilize the nanoparticles in addition to lowering the gold ions. To further improve these AuNPs' stability and biocompatibility, we functionalized them using polyvinyl pyrrolidone (PVP). The effective synthesis and functionalization of the produced PVP-b-AuNPs were confirmed by characterization utilizing FTIR, HR-TEM, XRD and UV-Vis spectroscopy. Biological evaluations revealed that PVP-b-AuNPs exhibit superior antioxidant and antimicrobial activities compared to unfunctionalized b-AuNPs. These findings highlight the potential of S. samarangense leaf extract in the sustainable synthesis of functionalized AuNPs, providing a scalable, eco-friendly alternative for applications in healthcare and other industries.
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Chaudhary et al. (2025) studied this question.
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