Randomized controlled trial compares efficacy and safety of intradetrusor injections and pharmacotherapy in refractory overactive bladder, suggesting effective treatment options.
No AccessJournal of UrologyReply to Letters to the Editor20 Aug 2025Reply: The Efficacy and Safety Between Intradetrusor OnabotulinumtoxinA Injection and Combined Pharmacotherapy in Patients With Refractory Overactive Bladder: A Randomized Controlled Trialis a reply to letterLetter: The Efficacy and Safety Between Intradetrusor OnabotulinumtoxinA Injection and Combined Pharmacotherapy in Patients With Refractory Overactive Bladder: A Randomized Controlled Trial Hui-Hsuan Lau Hui-Hsuan LauHui-Hsuan Lau https://orcid.org/0000-0003-3620-9298 Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, Taiwan on behalf of the authors View All Author Informationhttps://doi.org/10.1097/JU.0000000000004700AboutFull TextPDF Cite Export CitationSelect Citation formatNLMAMAIEEEACMAPAChicagoMLAHarvardTips on citation downloadDownload citationCopy citation ToolsAdd to favoritesTrack Citations ShareFacebookLinked InTwitterEmail "Reply: The Efficacy and Safety Between Intradetrusor OnabotulinumtoxinA Injection and Combined Pharmacotherapy in Patients With Refractory Overactive Bladder: A Randomized Controlled Trial." The Journal of Urology, Publish Ahead of Print, pp. REFERENCES 1. . Letter to the editor: The efficacy and safety between intradetrusor onabotulinumtoxinA injection and combined pharmacotherapy in patients with refractory overactive bladder: a randomized controlled trial. J Urol.2025; 00(00):000-000. doi: 10.1097/JU.0000000000004699 Link, Google Scholar 2. ; 191622-096 Investigators. Durable efficacy and safety of long-term onabotulinumtoxinA treatment in patients with overactive bladder syndrome: final results of a 3.5-year study. J Urol.2016; 196(3):791-800. doi: 10.1016/j.juro.2016.03.146 Link, Google Scholar 3. . Efficacy and safety of combining mirabegron with solifenacin in patients with overactive bladder: a randomized, double-blind, placebo-controlled study (SYMPHONY). BJU Int.2015; 116(4):595-605. Google Scholar 4. . OnabotulinumtoxinA vs sacral neuromodulation on refractory urgency urinary incontinence in women: a randomized clinical trial. JAMA.2016; 316(13):1366-1374. doi: 10.1001/jama.2016.14617 Crossref, Medline, Google Scholar 5. . The efficacy and safety between intradetrusor onabotulinumtoxinA injection and combined pharmacotherapy in patients with refractory overactive bladder: a randomized controlled trial. J Urol.2025; 00(00):000-000. doi: 10.1097/JU.0000000000004660 Link, Google Scholar Funding/Support: None. Conflict of Interest Disclosures: The Author has no conflicts of interest to disclose. Author Contributions: Conception and design: Lau. Drafting the manuscript: Lau. Supervision: Lau. © 2025 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsRelated articlesJournal of Urology13 Aug 2025Letter: The Efficacy and Safety Between Intradetrusor OnabotulinumtoxinA Injection and Combined Pharmacotherapy in Patients With Refractory Overactive Bladder: A Randomized Controlled Trial Advertisement Copyright & Permissions© 2025 by American Urological Association Education and Research, Inc. Author Information Hui-Hsuan Lau Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, Taiwan More articles by this author Expand All Funding/Support: None. Conflict of Interest Disclosures: The Author has no conflicts of interest to disclose. Author Contributions: Conception and design: Lau. Drafting the manuscript: Lau. Supervision: Lau. Advertisement PDF downloadLoading ...
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