Endoscopic submucosal dissection of uncommon huge gastric pyloric gland adenoma

Pyloric gland adenoma (PGA) is a rare gastrointestinal tumor that is characterized by dense packing of gastric pyloric glands with occasional cystic dilatation [1]. PGAs represent almost 2.7% of all gastric polyps with a conversion rate of 47% to invasive adenocarcinoma [2]. There are currently no evidence-based recommendations on resection technique and surveillance protocol specific for PGAs. Previously reported large gastric PGA was treated with laparoscopic resection [1]. However, endoscopic submucosal dissection (ESD) has been recently used in the treatment of smaller PGAs [3] [4]. Herein, we report a rare case of huge gastric PGA treated with ESD.