PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
September 10, 2025Aging Clinical and Experimental Research0 citationsOpen Access

Multimorbidity Patterns Affect Mortality in Older Adults: Insights from Two Cohorts

Multimorbidity patterns and mortality in older adults: a two-cohort pooled analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

CDCecilia DamianoSCSimona CostanzoBMBenedetta Marcozzi

Discussion

Loading...

Member takes

Overview

Pooled analysis reveals distinct multimorbidity patterns increase mortality risk in older adults, suggesting targeted interventions.

Key Points

  • Cardiometabolic and respiratory multimorbidity pattern is linked to the highest mortality risk, suggesting urgent clinical attention is needed.
  • Overall mortality rates were 1.66 per 100 person/years in CUORE and 1.85 in Moli-sani, emphasizing significant health challenges.
  • Latent Class Analysis identified six distinct multimorbidity patterns that are indicative of different health risks among older individuals.
  • Cox regression revealed that higher mortality risks are associated with specific multimorbidity patterns, guiding clinical management strategies.

Cite This Study

Damiano et al. (2025) studied this question.

synapsesocial.com/papers/68c1cc3754b1d3bfb60f4660https://doi.org/10.1007/s40520-025-03150-0
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multimorbidity patterns and trajectories in young and middle-aged adults: a large-scale population-based cohort study2024 · 27 citations
  2. 2Multimorbidity Patterns and Mortality Risk in a National Sample of US Adults Identified Using Latent Class Analysis2026
  3. 3Multimorbidity as specific disease combinations, an important predictor factor for mortality in octogenarians: the Octabaix study2017 · 48 citations
  4. 4Association of multimorbidity and its patterns with risk of mortality among the elderly in Shenzhen, China2026
  5. 5Multimorbidity, disease clusters and risk of all-cause and cause-specific mortality: a population-based prospective cohort study2025