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September 10, 2025BMC GastroenterologyOpen Access

Mucosal microbiota signatures reveal diagnostic insights in chronic liver disease

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Observational analysis reveals distinct microbial signatures in chronic liver disease patients, suggesting diagnostic potential.

Significant differences in gut microbiota composition between chronic liver disease patients and healthy controls were observed.
Metagenomic analysis showed increased levels of Proteobacteria in chronic liver disease, while Firmicutes predominated in controls.
Alpha diversity was significantly lower in chronic liver disease patients, indicating reduced microbial richness compared to controls.
The integration of metagenomic findings with biochemical markers highlights unique microbial profiles in chronic liver disease.

Dinçer et al. (2025) studied this question.

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