Analysis reveals potential therapeutic targets and biomarkers in testicular germ cell tumors, highlighting resistance to chemotherapy.
Introduction The most prevalent solid cancer in young adult males is testicular germ cell tumors (TGCTs), which are becoming more and more common globally. Approximately 20% of patients with metastatic disease relapse or develop resistance to cisplatin-based chemotherapy, despite its high effectiveness, underscoring the need for alternative therapies.
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Esposito et al. (2025) studied this question.
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