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September 10, 2025Sports MedicineOpen Access

Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners

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Authors

JWJamie WhitfieldAMAlannah K. A. McKayNTNicolin Tee

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Overview

Double-blind trial evaluated urolithin A's effects on performance and mitochondrial biomarkers in runners, suggesting potential recovery benefits.

Key Points

  • Urolithin A supplementation improved recovery metrics, reducing muscle damage markers following exercise.
  • Supplementation showed a significant increase in aerobic capacity (5.4%) but did not enhance overall running performance.
  • The clinical trial involved 42 highly trained male distance runners over a four-week period during altitude training.
  • Findings suggest potential for urolithin A to support recovery processes in endurance athletes, despite limited performance gains.

Cite This Study

Whitfield et al. (2025) studied this question.

synapsesocial.com/papers/68c1ce5d54b1d3bfb60f5213https://doi.org/10.1007/s40279-025-02292-5
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