The prevalence and risk factors of hyperuricemia in patients with Newly-diagnosed coronary artery disease from 2017 to 2021

This study aimed to evaluate the prevalence and determinants of hyperuricemia in patients with newly-diagnosed coronary artery disease (CAD) after percutaneous coronary intervention. Hyperuricemia was defined as a serum urate level of > 5.6 mg/dl. Medical records and face-to-face interviews were used to collect the demographic characteristics, medical history, lifestyle, self-management, physical examination, and laboratory examination information for each patient. Logistic regression was then used to assess the associations between hyperuricemia and several independent risk factors. The regression results showed that the overall prevalence of hyperuricemia was 43.2% (42.0% in men and 47.0% in women) and gender, hypertension, triglycerides, body mass index (BMI) and HbA1c were risk factors for hyperuricemia. Our findings suggest that the prevalence of hyperuricemia is very high in newly-diagnosed CAD patients after percutaneous coronary intervention (PCI), but the associated risk factors we identified can be ameliorated by diet and lifestyle changes.