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This is a Observational study (also classified as: Animal Study).

September 10, 2025Microbiological ResearchOpen Access

Biological Characterization and Stability of Three Lytic Wastewater-Derived Bacteriophages Targeting Multi-Drug Resistant Acinetobacter baumannii and A. johnsonii Clinical Strains

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Three lytic bacteriophages were isolated from sewage samples and characterized for their stability and efficacy against multidrug-resistant Acinetobacter species.
Genomic analysis confirmed that these phages, Acba_19, Acjo_20, and Acba_21, lack temperate markers, classifying them as strictly lytic viruses.
Stability studies revealed the effects of pH, temperature, and different cryoprotectants on phage preparations across various storage conditions.
These findings suggest a promising alternative approach to combat multi-drug resistant pathogens in clinical settings.

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Implication

This analysis reports on the stability and effectiveness of bacteriophages against multi-drug resistant Acinetobacter baumannii and A. johnsonii, highlighting their therapeutic potential.

Cite This Study

Cieślik et al. (2025) studied this question.

synapsesocial.com/papers/68c1ce6754b1d3bfb60f579c https://doi.org/10.1016/j.micres.2025.128320

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Implication

This analysis reports on the stability and effectiveness of bacteriophages against multi-drug resistant Acinetobacter baumannii and A. johnsonii, highlighting their therapeutic potential.

Biological Characterization and Stability of Three Lytic Wastewater-Derived Bacteriophages Targeting Multi-Drug Resistant Acinetobacter baumannii and A. johnsonii Clinical Strains

Key Points

Discussion

Implication

Cite This Study

Biological Characterization and Stability of Three Lytic Wastewater-Derived Bacteriophages Targeting Multi-Drug Resistant Acinetobacter baumannii and A. johnsonii Clinical Strains

Key Points

Discussion

Implication

Cite This Study

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