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September 10, 2025Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina VeterináriaOpen Access

Tracheal mast cell tumor in a dog – surgical approach and diagnosis

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Authors

FSFernanda Rezende SouzaUniversidade Federal de Minas GeraisKNKaren Yumi Ribeiro NakagakiUniversidade Federal de Minas GeraisFMFernanda Freitas Miranda

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Overview

Case report describes surgical approach and immunohistochemical features of mast cell tumors in dogs, indicating complexity in diagnosis.

Key Points

  • Tracheal mast cell tumor surgery resulted in no immediate complications, but later the dog suffered a local recurrence.
  • Histopathological analysis confirmed neoplastic proliferation and immunohistochemistry indicated high levels of Ki67 positivity.
  • An 8-year-old dog with dyspnea and choking was found to have a mass obstructing the trachea requiring surgical removal.
  • Mast cell tumors should be included in the differential diagnosis for dogs presenting with extracutaneous masses or nodules.

Cite This Study

Souza et al. (2025) studied this question.

synapsesocial.com/papers/68c1ce7b54b1d3bfb60f5c2chttps://doi.org/10.29374/2527-2179.bjvm000525
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Use of KIT and Tryptase Expression Patterns as Prognostic Tools for Canine Cutaneous Mast Cell Tumors2004 · 259 citations
  2. 2Canine Mast Cell Tumors: Correlation of Apoptosis and Proliferation Markers with Prognosis2006 · 41 citations
  3. 3Immunohistochemical detection of proliferating cell nuclear antigen and Ki-67 in mast cell tumors from dogs1999 · 151 citations
  4. 4Recurrence rates and clinical outcome for dogs with grade II mast cell tumours with a low AgNOR count and Ki67 index treated with surgery alone2015 · 36 citations
  5. 5Intranasal mast cell tumors: Clinical, immunohistochemical, and molecular features in 20 dogs2022 · 4 citations