This analysis shows METTL14 and YTHDF1 impact ASMC behavior under PDGF-BB treatment, indicating their regulatory roles.
Background Increased proliferation and migration of abnormal airway smooth muscle cells (ASMCs) are significantly associated with asthma. This study aimed to investigate the effects of methyltransferase-like 14 (METTL14), YTH domain-containing family Protein 1 (YTHDF1), and polypyrimidine tract-binding protein 1 (PTBP1) on platelet-derived growth factor-BB (PDGF-BB)-treated ASMCs.
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Qiu et al. (2025) studied this question.
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