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September 10, 2025CureusOpen Access

Retrospective Analysis of the Uptake and Timing of Risk-Reducing Salpingo-Oophorectomy in Women With BRCA1/2 Pathogenic Variants

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Age over 45 and a history of breast cancer significantly increase the likelihood of choosing RRSO.
Nearly half of the women in the study underwent RRSO, with BRCA1 carriers more likely to have early surgery.
Statistical analyses determined the relationship between personal factors and surgical timing.
The study emphasizes the need for personalized counseling based on individual risk factors.

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Retrospective analysis reveals factors influencing RRSO uptake and timing in women with BRCA1/2, suggesting individualized counseling is vital.

Hasegawa et al. (2025) studied this question.

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Retrospective analysis reveals factors influencing RRSO uptake and timing in women with BRCA1/2, suggesting individualized counseling is vital.