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September 10, 2025Journal of Inflammation ResearchOpen Access

Time-Course Renal and Pulmonary Injury Analysis and Bioinformatics Screening of Core Pathogenic Genes and Immune Cell Infiltration Patterns in a Sepsis

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Authors

AAAnwaier ApiziXinjiang Medical UniversityJLJian LiXinjiang Medical UniversityPKPaiheriding KamilijiangXinjiang Medical University

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Implication

This study evaluates organ damage in sepsis and identifies core genes and immune cell differences.

Key Points

  • Sepsis caused significant lung and kidney damage over time, highlighting the need for better management.
  • The study identified 505 core genes and constructed a predictive model utilizing five key genes for sepsis risk.
  • Observational methods found differences in immune cell composition, indicating the role of T cells and dendritic cells.
  • The analysis of gene expression patterns sheds light on sepsis-related pathways and their immunological implications.

Cite This Study

Apizi et al. (2025) studied this question.

synapsesocial.com/papers/68c1d03554b1d3bfb60f6f1fhttps://doi.org/10.2147/jir.s530849
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