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September 10, 2025Molecular CancerOpen Access

Single-cell multi-omics in cancer immunotherapy: from tumor heterogeneity to personalized precision treatment

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Authors

JLJiayuan LeCentral South UniversityYDYating DianCentral South UniversityDZDeze ZhaoCentral South University

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Implication

This review highlights tumor heterogeneity and immune escape in cancer, suggesting advances in precision oncology.

Key Points

  • Precision oncology can be enhanced through single-cell multi-omics technologies, improving treatment outcomes for cancer.
  • Recent developments in single-cell sequencing uncover immune escape and treatment resistance within heterogeneous tumors.
  • These approaches illuminate patient-specific immune responses, offering insights vital for personalizing cancer therapies.
  • Current challenges include technical limitations of single-cell technologies, which impede broader application in clinical settings.

Cite This Study

Le et al. (2025) studied this question.

synapsesocial.com/papers/68c1d03e54b1d3bfb60f7021https://doi.org/10.1186/s12943-025-02426-3
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