Editorial for “Genetic Susceptibility to Cardio‐Cerebrovascular Diseases and White Matter Integrity in Asymptomatic Older Adults: A UK Biobank Observational Cohort Study”

Journal of Magnetic Resonance ImagingEarly View EDITORIAL Editorial for "Genetic Susceptibility to Cardio-Cerebrovascular Diseases and White Matter Integrity in Asymptomatic Older Adults: A UK Biobank Observational Cohort Study" This article relates to: Genetic Susceptibility to Cardio-Cerebrovascular Diseases and White Matter Integrity in Asymptomatic Older Adults: A UK Biobank Observational Cohort Study Jingchun Liu, Caihong Wang, Yujie Zhang, Wen Qin, Chunshui Yu, Journal of Magnetic Resonance Imaging First Published online: July 12, 2025 Song Liu, Song Liu orcid.org/0000-0002-5154-3115 Department of Radiology, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, ChinaSearch for more papers by this authorShuang Xia, Corresponding Author Shuang Xia [email protected] orcid.org/0000-0003-1626-6383 Department of Radiology, First Central Hospital of Tianjin Medical University, Tianjin, China Correspondence: Shuang Xia ([email protected])Search for more papers by this author Song Liu, Song Liu orcid.org/0000-0002-5154-3115 Department of Radiology, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, ChinaSearch for more papers by this authorShuang Xia, Corresponding Author Shuang Xia [email protected] orcid.org/0000-0003-1626-6383 Department of Radiology, First Central Hospital of Tianjin Medical University, Tianjin, China Correspondence: Shuang Xia ([email protected])Search for more papers by this author First published: 25 August 2025 https://doi.org/10.1002/jmri.70100Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky No abstract is available for this article. References 1A. V. Khera, M. Chaffin, K. H. Wade, et al., "Polygenic Prediction of Weight and Obesity Trajectories From Birth to Adulthood," Cell 177, no. 3 (2019): 587–596.e9. 10.1016/j.cell.2019.03.028 CAS PubMed Web of Science® Google Scholar 2L. T. Elliott, K. Sharp, F. Alfaro-Almagro, et al., "Genome-Wide Association Studies of Brain Imaging Phenotypes in UK Biobank," Nature 562, no. 7726 (2018): 210–216. 10.1038/s41586-018-0571-7 CAS PubMed Web of Science® Google Scholar 3C. Yu, J. Liu, C. Wang, Y. Zhang, and W. Qin, "Genetic Susceptibility to Cardio-Cerebrovascular Diseases and White Matter Integrity in Asymptomatic Older Adults: A UK Biobank Observational Cohort Study," Journal of Magnetic Resonance Imaging (2025), https://doi.org/10.1002/jmri.70042. 10.1002/jmri.70042 Web of Science® Google Scholar 4B. Zhao, T. Li, Y. Yang, et al., "Common Genetic Variation Influencing Human White Matter Microstructure," Science 372, no. 6548 (2021): eabf3736. 10.1126/science.abf3736 CAS PubMed Web of Science® Google Scholar 5F. Yi, J. Yuan, J. Somekh, et al., "Genetically Supported Targets and Drug Repurposing for Brain Aging: A Systematic Study in the UK Biobank," Science Advances 11, no. 11 (2025): eadr3757. 10.1126/sciadv.adr3757 PubMed Web of Science® Google Scholar 6Z. Shirzadi, S. A. Schultz, W. W. Yau, et al., "Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease," JAMA Neurology 80, no. 12 (2023): 1353–1363. 10.1001/jamaneurol.2023.3618 PubMed Web of Science® Google Scholar 7W. Q. Huang, Q. Lin, and C. M. Tzeng, "Leukoaraiosis: Epidemiology, Imaging, Risk Factors, and Management of Age-Related Cerebral White Matter Hyperintensities," Journal of Stroke 26, no. 2 (2024): 131–163. 10.5853/jos.2023.02719 PubMed Web of Science® Google Scholar 8H. Li, C. Chai, Y. Xie, et al., "Disturbed Neurovascular Coupling in Patients With White Matter Hyperintensities: Potential Biomarker for Cognitive Impairment," Neuroradiology 66, no. 11 (2024): 1967–1978. 10.1007/s00234-024-03459-z PubMed Web of Science® Google Scholar 9H. Li, Y. Li, Q. Zhong, et al., "Dysfunction of Neurovascular Coupling in Patients With Cerebral Small Vessel Disease: A Combined Resting-State fMRI and Arterial Spin Labeling Study," Experimental Gerontology 194 (2024): 112478. 10.1016/j.exger.2024.112478 PubMed Web of Science® Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation