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September 10, 2025Journal of Neuropsychiatry

Mild Behavioral Impairment: A Population-Based Study

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Authors

MVMaria VassilakiWinnMedJSJeremy A. SyrjanenKarlsruhe Institute of TechnologyJKJanina Krell-Roesch

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Implication

Population-based study reveals links between mild behavioral impairment, cognitive decline, and neuropsychiatric symptoms in older adults.

Key Points

  • Participants with mild behavioral impairment were over three times more likely to have mild cognitive impairment.
  • The study revealed that 11% of older adults had mild behavioral impairment at the first follow-up.
  • Cross-sectional analysis employed linear and logistic regression to adjust for key factors like age and sex.
  • Findings highlight a potential precursor effect of mild behavioral impairment on cognitive decline.

Cite This Study

Vassilaki et al. (2025) studied this question.

synapsesocial.com/papers/68c1d23054b1d3bfb60f7a7ehttps://doi.org/10.1176/appi.neuropsych.20240155
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neuropsychiatric symptoms and the outcome of cognitive trajectories in older adults free of dementia: The Mayo Clinic Study of Aging2021 · 45 citations
  2. 2The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations2017 · 570 citations
  3. 3Mild behavioral impairment: measurement and clinical correlates of a novel marker of preclinical Alzheimer’s disease2022 · 123 citations
  4. 4Optimizing detection of Alzheimer’s disease in mild cognitive impairment: a 4-year biomarker study of mild behavioral impairment in ADNI and MEMENTO2023 · 84 citations
  5. 5Gender/Sex Differences in the Association of Mild Behavioral Impairment with Cognitive Aging2022 · 63 citations