Disagreement between self- and informant-reported memory complaints and progression of mild cognitive impairment to dementia

Patrícia Regueira; Inês Baldeiras; Marisa Lima; Miguel Tábuas‐Pereira; Diana Duro; Anuschka Silva‐Spínola; Joaquim Cerejeira; Isabel Santana

doi:10.1080/13607863.2025.2552425

August 26, 2025Aging & Mental Health

Disagreement between self- and informant-reported memory complaints and progression of mild cognitive impairment to dementia

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Key Points

Discrepancy in memory reports effectively predicts conversion from mild cognitive impairment to dementia, indicating impaired awareness is critical.
Key evidence shows that disparities between patient and informant reported memory deficits can serve as a reliable prognostic tool.
Assessment involved comparing self-reports from patients with informant data in a cohort of individuals with mild cognitive impairment.
Highlighting the necessity for further research on diagnostic criteria and intervention strategies in MCI populations.

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Implication

Observational analysis evaluates the impact of discrepancies in memory complaints on dementia conversion in MCI patients, suggesting awareness may play a key role.

Abstract

Objectives To evaluate whether discrepancy between patient and informant reports of memory deficits can be used as a proxy of impaired awareness of memory function in Mild Cognitive Impairment (MCI) and to determine its prognostic value in conversion to dementia.

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Cite This Study

Regueira et al. (2025) studied this question.

synapsesocial.com/papers/68c1d23054b1d3bfb60f7caa https://doi.org/10.1080/13607863.2025.2552425

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Disagreement between self- and informant-reported memory complaints and progression of mild cognitive impairment to dementia

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Disagreement between self- and informant-reported memory complaints and progression of mild cognitive impairment to dementia

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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