Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Open Access

Long-term Safety and Efficacy of Ixekizumab in Patients With Moderate to Severe Psoriasis – a Systematic Review of Randomised Controlled Trials

View Full Paper
Ask AI
Bookmark
Share

Authors

SSSukesh Gautam ShankarNJNaomi Jeyaraj

Discussion

Loading...

Member takes

Overview

Systematic review highlights ixekizumab's safety and efficacy in treating psoriasis, comparing outcomes to placebo.

Key Points

  • Ixekizumab demonstrated superior efficacy in improving PASI scores compared to placebo, suggesting it is effective for psoriasis treatment.
  • Among 4705 participants in 6 trials, most adverse events reported were mild, indicating a favorable safety profile.
  • Systematic review followed PRISMA guidelines and included only randomised clinical trials, ensuring robust results.
  • Despite its efficacy, ixekizumab's usage remains relatively lower than conventional immunomodulatory agents in psoriasis management.

Cite This Study

Shankar et al. (2025) studied this question.

synapsesocial.com/papers/68c1d5ef54b1d3bfb60f8a9ehttps://doi.org/10.21203/rs.3.rs-7458832/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real-World Efficacy and Safety of Ixekizumab in the Treatment of Psoriasis: A Case-Series from Indian Sub-Continent2026
  2. 2The effectiveness and safety of ixekizumab in psoriasis patients under clinical practice conditions: A Spanish multicentre retrospective study2020 · 12 citations
  3. 3Long-Term Effectiveness and Safety of Ixekizumab for the Treatment of Moderate-to-Severe Plaque Psoriasis: A Five-Year Multicenter Retrospective Study—IL PSO (Italian Landscape Psoriasis)2024 · 7 citations
  4. 4Advantages of IL-17 inhibitor, ixekizumab, in the treatment of severe psoriasis2024
  5. 5Real-World Efficacy and Safety of Ixekizumab from the Joint Psoriasis-Psoriatic Arthritis Clinic (PPAC)2026