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September 10, 2025Journal of Radiation ResearchOpen Access

Clinical outcomes and prognostic factors of adjuvant radiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study

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Authors

KTKeisuke TsuchidaKAKen AndoNONoriyuki Okonogi

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Overview

Nationwide survey analyzes adjuvant radiotherapy's impact on survival in vulvar cancer patients, suggesting key prognostic factors.

Key Points

  • Advanced age and higher nodal burden were identified as significant negative predictors of survival outcomes.
  • The 5-year overall survival was 71.8% for stage I and dropped to 47.3% for stage IV vulvar cancer patients.
  • Survival outcomes were evaluated using the Kaplan-Meier method along with univariate and multivariate analyses.
  • Findings highlight the need for tailored treatment strategies based on age and lymph node involvement.

Cite This Study

Tsuchida et al. (2025) studied this question.

synapsesocial.com/papers/68c1d5f754b1d3bfb60f8ee1https://doi.org/10.1093/jrr/rraf050
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries2021 · 114,700 citations
  2. 2European Society of Gynaecological Oncology Guidelines for the Management of Patients with Vulvar Cancer - Update 20232023 · 226 citations
  3. 3Global incidence, risk factors and trends of vulvar cancer: A country‐based analysis of cancer registries2023 · 31 citations