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September 10, 2025Open Access

Origami Paper-based tecHnology fOr the innovativE aNd sustaInable organ-on-chip devices

FAFabiana ArduiniUniversity of Rome Tor Vergata JRJavier RamonInstitute for Bioengineering of Catalonia KHKersti HermanssonUppsala University

Key Points

This project develops sustainable, origami-inspired organ-on-chip devices that integrate biosensors for monitoring cellular responses.
The research focuses on making drug testing more accessible and cost-effective, reducing reliance on traditional animal models.
Interdisciplinary collaboration among six European partners drives innovations in biomedical research and personalised medicine.
The use of paper-based technology highlights the potential for sustainable approaches in medical device development.

Abstract

Origami Paper-based tecHnology fOr the innovativE aNd sustaInable organ-on-chip devices PHOENIX-OoC develops sustainable, origami-inspired paper-based organ-on-a-chip devices integrating (bio)sensors for real-time monitoring of cellular responses. It aims to make drug testing more accessible, cost-effective and accurate, reducing reliance on animal models. Through interdisciplinary collaboration among six European partners, the project advances biomedical research and personalised medicine.

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