What type of study is this?

September 10, 2025StrokeOpen Access

Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study

View Full Paper

Ask AI

Bookmark

Authors

MDMohamed Fahmy DoheimUniversity of Pittsburgh RKRobrecht R. M. M. KnapenMaastricht University Medical Centre JSJulie StaalsMaastricht University Medical Centre

Discussion

Member takes

Implication

Observational analysis shows that bridging therapy may improve functional outcomes in acute ischemic stroke patients, suggesting it can be a better choice than EVT alone.

Key Points

Bridging therapy significantly reduces disability at 90 days compared to EVT alone, highlighting its potential effectiveness.
At 90 days, the adjusted common odds ratio for mRS score between IVT+EVT and EVT alone is 1.52, implying better outcomes with bridging therapy.
This analysis involved 539 patients with M2 segment occlusions, providing robust insights into treatment efficacy and safety.
Findings suggest bridging therapy may lead to improved functional outcomes, though recanalization and hemorrhage rates were not statistically significant.

Cite This Study

Doheim et al. (2025) studied this question.

synapsesocial.com/papers/68c1d60654b1d3bfb60f971f https://doi.org/10.1161/strokeaha.125.051967

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis shows that bridging therapy may improve functional outcomes in acute ischemic stroke patients, suggesting it can be a better choice than EVT alone.

Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider