Prospective study shows significant reductions in intraocular pressure and anti-glaucoma medications in Indian glaucoma patients, suggesting KDB's effectiveness.
Purpose: To assess the success rate and complications of Kahook Dual Blade (KDB) procedure in Indian patients diagnosed with glaucoma. Methods: This prospective study was done on 68 Indian patients who underwent KDB procedure combined with phacoemulsification. Baseline demographic and clinical characteristics were recorded, including visual acuity, intraocular pressure (IOP), number of anti-glaucoma medications (AGM), and complications. Follow-up assessments were conducted regularly over 1 year, evaluating changes in IOP, visual acuity, medication usage, and occurrence of adverse events. Results: KDB procedure demonstrated significant reductions in mean ± SD IOP from baseline (17.2 ± 5.9) to 1 year (14.1 ± 3.5) ( P < 0.001). This was accompanied by improvements in mean ± SD BCVA of 0.7 ± 0.7 preoperatively to 0.2 ± 0.5 postoperatively ( P < 0.001). Simultaneously, there were significant reductions in the median (IQR) number of AGM from 2 (1–4) at the preoperative level to 1 (0–1) at 1 year ( P < 0.001). A common adverse effect noted was hyphema (n = 11), which was self-resolving in 10 out of 11 cases, with one case needing anterior chamber wash. Conclusion: KDB procedure shows promising outcomes, as evidenced by significant reductions in IOP and decreased dependence on AGM at 1-year follow-up. Further long-term studies are warranted to assess the sustained efficacy and safety profile of the KDB procedure in this patient population.
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Bhumbla et al. (2025) studied this question.
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