Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025BiomoleculesOpen Access

Antibiofilm Inhibitor Ferulic Acid as an Antibacterial Synergist Against Escherichia coli

View Full Paper
Ask AI
Bookmark
Share

Authors

ZZZhijin ZhangHebei University of EngineeringJXJing XuLanzhou Institute of Husbandry and Pharmaceutical SciencesXWXiaojuan WeiLanzhou Institute of Husbandry and Pharmaceutical Sciences

Discussion

Loading...

Member takes

Implication

Research demonstrates ferulic acid inhibits biofilm formation and shows synergy with antibiotics against E. coli, suggesting it as a potential treatment.

Key Points

  • Ferulic acid significantly inhibits biofilm formation of escherichia coli, improving antibacterial strategies.
  • The alamar blue assay showed that ferulic acid has a strong synergistic effect with sodium fosfomycin against bacteria.
  • qRT-PCR analysis indicates ferulic acid alters gene expression rates related to biofilm formation and motility.
  • These findings suggest that ferulic acid could serve as a promising adjunct therapy to traditional antibiotics.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c1d7f654b1d3bfb60fa0e8https://doi.org/10.3390/biom15091253
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reference Genes for Expression Analyses by qRT-PCR in Enterobacter cancerogenus2024 · 7 citations
  2. 2Synergistic interactions of ionic liquids and antimicrobials improve drug efficacy2020 · 46 citations
  3. 3Type I fimbriae subunit fimA enhances Escherichia coli biofilm formation but affects L-threonine carbon distribution2022 · 17 citations
  4. 4The Role of the Bacterial Flagellum in Adhesion and Virulence2013 · 617 citations
  5. 5Flagellar Motility During E. coli Biofilm Formation Provides a Competitive Disadvantage Which Recedes in the Presence of Co-Colonizers2022 · 32 citations