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September 10, 2025Scientific ReportsOpen Access

Comparative evaluation of large language models performance in medical education using urinary system histology assessment

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Performance of large language models varied significantly, with ChatGPT-o1 achieving the highest MCQ accuracy at 96.31%.
Clinical scenario generation was led by Claude-3.5, scoring 91.4% of the maximum, highlighting different strengths across tasks.
Evaluation employed two independent tasks—MCQ performance and scenario generation—using a multi-dimensional framework for quality metrics.
Findings underscore the necessity of aligning model capabilities with educational goals to enhance effective implementation in medical education.

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Comparative assessment of LLMs in urinary histology shows varying performance, indicating tailored educational tasks are essential.

Szabó et al. (2025) studied this question.

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