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September 10, 2025Journal of health economics and outcomes researchOpen Access

Healthcare Resource Use, Healthcare Costs, and Unmet Needs Among Patients Treated for EGFR-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

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Authors

DWDavid WaterhouseILI. А. LiLMLaura Morrison

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Overview

Observational analysis reports costs and resource use in EGFRm advanced NSCLC patients, suggesting critical unmet needs.

Key Points

  • Each successive line of therapy resulted in increased healthcare costs and reduced duration of treatment.
  • Patients initiating first-line osimertinib had average costs of $27,610, which increased significantly in second and third-line therapies.
  • The analysis highlighted that 41.6% of patients progressed to the second line, with subsequent costs averaging $28,971 in the second line.
  • Mean outpatient visits were over four per month, particularly pronounced in the first-line osimertinib subgroup, reflecting significant healthcare resource use.

Cite This Study

Waterhouse et al. (2025) studied this question.

synapsesocial.com/papers/68c1d80554b1d3bfb60fa80chttps://doi.org/10.36469/jheor.2025.142771
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Also Consider

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  1. 1Overall Survival with Osimertinib in Untreated, <i>EGFR</i> -Mutated Advanced NSCLC2019 · 2,937 citations
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  5. 5Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer2019 · 380 citations