What type of study is this?

This is a Systematic Review study (also classified as: Network Meta-Analysis).

September 10, 2025PeerJOpen Access

Surgery, radiotherapy and endocrine therapy for oligometastatic prostate cancer efficacy: a systematic review and network meta-analysis

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Authors

WYWenwei YingPeking University ZDZhenshan DingChina-Japan Friendship Hospital YHYuhui HeSouth China Agricultural University

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Implication

Network meta-analysis reveals benefits of combination therapies over androgen-deprivation therapy alone, suggesting improved outcomes in oligometastatic prostate cancer.

Key Points

Combination therapies like ADT+RT significantly improved progression-free survival over ADT alone.
The analysis involved 2,524 patients across 13 trials, highlighting the efficacy of combined treatments.
Limited quality of life data suggest ADT+RT may provide slight improvements, with more research needed.
Safety analysis showed ADT alone had the lowest risk of adverse events, but combination therapies may increase toxicity.

Cite This Study

Ying et al. (2025) studied this question.

synapsesocial.com/papers/68c1d97d54b1d3bfb60fb14c https://doi.org/10.7717/peerj.19819

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Implication

Network meta-analysis reveals benefits of combination therapies over androgen-deprivation therapy alone, suggesting improved outcomes in oligometastatic prostate cancer.

Surgery, radiotherapy and endocrine therapy for oligometastatic prostate cancer efficacy: a systematic review and network meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Surgery, radiotherapy and endocrine therapy for oligometastatic prostate cancer efficacy: a systematic review and network meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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