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September 10, 2025Surgical Neurology International

Evaluating the role of surgical timing on clinical outcomes in traumatic spinal cord injury: A systematic review and meta-analysis

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Authors

TNTommy Alfandy NazwarFBFarhad Bal’afifDWDonny Wisnu Wardhana

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Overview

Systematic review evaluates surgical timing effects on neurological outcomes in traumatic spinal cord injury, suggesting early intervention improves recovery.

Key Points

  • Ultra-early surgery (≤12 h) significantly improves neurological outcomes compared to surgery after 12 h.
  • Surgery within 24 h outperforms delayed surgery (>24 h), indicating timely interventions are crucial.
  • Early surgical intervention leads to reduced hospital stay duration by approximately 5 days, without raising complications.
  • Long-term motor outcomes are favored in patients who undergo surgery within 24 hours post-injury.

Cite This Study

Nazwar et al. (2025) studied this question.

synapsesocial.com/papers/68c1d97d54b1d3bfb60fb161https://doi.org/10.25259/sni_678_2025
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Timing of Decompressive Surgery in Patients With Acute Spinal Cord Injury: Systematic Review Update2024 · 57 citations
  2. 2Ultra-early decompression and prevention of secondary injury in traumatic spinal cord injury: A single-center study2026
  3. 3An Update of a Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role and Timing of Decompressive Surgery2024 · 72 citations
  4. 4461 Outcomes and Healthcare Utilization of Adult Spinal Cord Injury Associated With Time to Surgery: An Analysis of the National Trauma Data Bank (NTDB): 2019-20212024
  5. 5Optimal Timing in Cervical Spinal Cord Injury: A Comprehensive Meta-Analysis of Ultra-Early Surgical Intervention Within Five Hours2024