Pediatric-onset Multiple Sclerosis in Families: A Distinct Phenotype

Multiple sclerosis (MS) is a chronic, immune-mediated disease of the central nervous system. Pediatric-onset MS (POMS) represents a distinct subgroup with unique clinical and immunological features. Although familial predisposition contributes to MS pathogenesis, data on familial POMS remain limited. To investigate the demographic and clinical characteristics of familial POMS and compare them with those of the broader MS patient cohort.