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Severe Neonatal Autoimmune Thrombocytopenia in a Mother with Chronic ITP After Splenectomy: Treated Successfully with IVIG, Case Report

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Case report shows successful use of intravenous immunoglobulin for thrombocytopenic neonate, highlighting implications for early detection.

Nadir platelet count reached 8,000/µL in a neonate, but treatment with intravenous immunoglobulin was effective.
The neonate’s platelet count increased to 348,000/µL after treatment, avoiding complications from severe thrombocytopenia.
Intravenous immunoglobulin served as the first-line treatment, indicating its vital role in managing neonatal autoimmune thrombocytopenia.
Early detection and monitoring of platelet counts are essential for improving outcomes in neonates with history of maternal ITP.

Endalew et al. (2025) studied this question.

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Case report shows successful use of intravenous immunoglobulin for thrombocytopenic neonate, highlighting implications for early detection.