Case report shows improved neurological symptoms after surgical resection of a pulmonary carcinoid tumor, suggesting underlying neoplasms may trigger PNS.
Paraneoplastic neurological syndromes (PNS) are a rare and heterogeneous group of immune-mediated neurological disorders. We report the case of a 32-year-old woman with progressive and severely disabling neurological symptoms. After excluding alternative causes, she was diagnosed with an atypical pulmonary carcinoid tumor. Surgical resection led to partial clinical improvement. This case underscores the importance of considering PNS in patients with unexplained neurological symptoms and highlights the need to investigate for underlying neoplasms as a potential trigger.
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Arroyave et al. (2025) studied this question.
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