A rare presentation of recurrent undifferentiated embryonal sarcoma of the liver with peritoneal and splenic metastases: case report and literature review

Undifferentiated embryonal sarcoma of the liver (UESL) is a rare, aggressive pediatric malignancy with a high recurrence rate. We present a case of a 16-year-old male with recurrent UESL and rare peritoneal and splenic metastases. Despite initial complete surgical resection, the tumor recurred, necessitating further surgeries and chemotherapy. PET-CT imaging played a crucial role in monitoring disease progression. This case highlights the importance of a multimodal approach, integrating surgery and systemic therapy, in managing recurrent UESL and underscores the need for long-term surveillance to improve patient outcomes.