The intra-breath changes of reactance at low frequency in impulse oscillometry: differentiating obstructive airway disease and Interstitial Lung Disease

Parthasarathi Bhattacharyya; Sayanti Karmakar; Wrick Chakraborty; Ranadip Pal

doi:10.1186/s12890-025-03835-2

August 30, 2025BMC Pulmonary MedicineOpen Access

The intra-breath changes of reactance at low frequency in impulse oscillometry: differentiating obstructive airway disease and Interstitial Lung Disease

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Key Points

Impulse oscillometry can distinguish obstructive airway disease from interstitial lung disease, achieving significant sensitivity and specificity.
Parameters including Xex5 and R5 showed considerable predictive capability, with areas under the curve of 0.9244 and 0.9292, respectively.
Significant differences were noted between healthy subjects and both obstructive and restrictive lung disease cohorts across various reactance metrics.
The Δintrabreath-X5 parameter demonstrated strong potential for differentiating interstitial lung disease from obstructive airway disease, needing further validation.

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Implication

Observational analysis identified key reactance parameters in obstructive airway disease and restrictive lung disease, suggesting potential diagnostic avenues.

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Bhattacharyya et al. (2025) studied this question.

synapsesocial.com/papers/68c1dd9b54b1d3bfb60fc1df https://doi.org/10.1186/s12890-025-03835-2

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The intra-breath changes of reactance at low frequency in impulse oscillometry: differentiating obstructive airway disease and Interstitial Lung Disease

Key Points

No abstract yet

Implication

Discussion

Cite This Study

The intra-breath changes of reactance at low frequency in impulse oscillometry: differentiating obstructive airway disease and Interstitial Lung Disease

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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